What is Esgic Plus?
Esgic Plus (Butalbital/Caffeine/Acetaminophen) is an analgesic,
barbiturate, and stimulant combination used to relieve complex tension
(muscle contraction) headaches. Precisely how the combination works is
What are the most common side effects
of Esgic Plus?
side effects of Esgic Plus include (but are not limited to): an
allergic reaction (difficulty breathing; closing of your throat; swelling of
your lips, tongue, or face; or hives); slow, weak breathing; liver damage (yellowing of the skin or eyes, nausea,
abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue);
blood problems (easy or unusual bleeding or bruising); low blood sugar (fatigue, increased hunger or thirst,
dizziness, or fainting.
Continue to take Esgic Plus if you experience drowsiness; dizziness, confusion or
lightheadedness shortness of breath, dry mouth; nausea, vomiting, abdominal
pain, or decreased appetite, tiredness, leg pain, or muscle weakness;
agitation, irritability, nervousness, anxiety or excitability rash or itching,
feeling of intoxication, headache; or constipation and contact your physician.
Other, less serious side effects may be more likely to occur.
How do I take Esgic Plus?
Esgic Plus should
be taken according to your physician’s directions. Take each dose of Esgic
Plus with a full glass of water.
What if I miss a dose?
Do not take a double dose of Esgic
Plus. Take the missed dose of Esgic Plus as soon as you remember.
If it is almost time for your next dose, skip the missed dose and go back
to taking Esgic Plus on your regular dosing schedule.
Are there any drug interactions with
Do not take Esgic Plus if you have taken a monoamine oxidase inhibitor in the last
14 days. Acetaminophen
and butalbital may increase the effects of other drugs that cause drowsiness,
including antidepressants, alcohol, antihistamines, sedatives (used to treat
insomnia), other pain relievers, anxiety medicines, and muscle relaxants. Tell
your doctor about all medicines that you are taking, and do not take any
medicine unless your doctor approves. Many other medicines contain
acetaminophen, especially over-the-counter pain, fever, cold, and allergy
medications. Too much acetaminophen can be very dangerous. Drugs other than
those listed here may also interact with Esgic Plus. Talk to your doctor and
pharmacist before taking any prescription or over-the-counter medicine.
Is there any additional information
about Esgic Plus that I should know?
Avoid sleeping pills, antihistamines, sedatives, and
tranquilizers except under the supervision of your doctor. These may also make
you drowsy Use caution when driving, operating machinery, or performing other
hazardous activities. Butalbital will cause drowsiness or dizziness. Avoid
alcohol. Alcohol taken during therapy with
acetaminophen and butalbital can be very damaging to your liver and can
increase drowsiness and dizziness. Never take more Esgic Plus than is
prescribed for you. If your pain is not being adequately treated, talk to your
How should I store Esgic Plus?
Store Esgic Plus at room temperature away
from moisture and heat. Keep out of reach of children.